Update : November 14, 2008    
Left main coronary
disease
Ostial disease
Bifurcation
Graft vessel disease
Diffuse coronary
disease
Chronic total
occlusion (CTO)
Restenosis
Multivessel disease
Drug eluting stent
Vulnerable plaque
International Case Presentation


Device Information
General Introduction
Slide for Features &
Benefits
Case Presentation
International Experience
AMC Experience
- Operator: Duncan Hung Kwong Ho, MD
Case summary

A 76 year-old gentleman presented with recurrent stable angina for 3 months. He had successful PTCA to proximal RCA more than 10 years ago and a 50% stenosis was also noted in the proximal LAD at that time. He has quitted smoking after a transient ischaemic attack in 2002. Hypercholesterolaemia was controlled with Lipitor.

Procedural steps

Coronary angiogram showed a critical stenosis in proximal LAD, at the bifurcation to D1 (Figure 1). A large cholesterol plaque overhung & prolapsed into the ostial D1. Diffused stenosis of about 50% was noted in the proximal to mid RCA (Figure 2). The LCX was small and subtotally occluded. The critical bifurcated lesion was first tackled and several strategies were to be considered:

1. Debulking with Flexicut and then stent the bifurcated lesion,
2.  Provisional T stenting with DES
3. Traditional crush stent technique with DES and finish with final kissing.

Since the D1 was relatively large and the angle between the main branch (LAD) and the side branch (D1) was less than 70 degrees (Figure 3), strategy 3 was adopted. I hope that restenosis rate of both vessels can be kept close to a single digit figure.

A 7F EBU3.5 guiding was used for a better backup support. The LAD was wired easily with a polymer hydrophilic coated Pilot 50 guidewire (Figure 4). However, the D1 was so difficult to be wired due to the overhanging plaque. The pLAD was first dilated with a cutting balloon 2.5 X 6 mm so as to change the geometry of the plaque at the bifurcation. Besides, the tip of another Pilot 50 GW was shaped like an "S" and then rotated into the D1 (Figure 5). Both the main branch and the side branch were adequately dilated with the cutting balloon. A Taxus 2.5 X 24 mm was placed from the LAD to the D1 and another Taxus 3.0 X 28 mm was placed from the proximal LAD to mid LAD (Figure 6). The D1 stent was deployed first and inflated up to 14 ATM and then the balloon and wire was withdrawn. The LAD stent was deployed with inflation pressure up to 12 ATM, crushing the D1 stent (Figure 7) against the wall of the main branch just proximal to the D1 ostium.

In order to achieve a lower restenosis rate at the side branch (35% to 12.5%, according to Colombo 's series), final kissing has to be done. So, the D1 was rewired easily with the Pilot 50 in the LAD and the LAD was wired again with the previously withdrawn guidewire. A Voyager 2.0 X 8 mm crossed the stent struts into the D1 without any difficulty (Figure 8). The cell was enlarged gradually. A second Voyager 2.5 X 15 mm was subsequently placed in the D1. Final kissing was completed by simultaneous inflation of another Voyager 3.0 X 20 mm in the LAD, both up to 14 ATM (Figure 9).

Final angiogram showed a very successful result without residual stenosis (Figure 10).

The most challenging part of the Crush technique is the rewiring and getting the balloon through the 2 layers of stent mesh at the bifurcation. Pilot 50 and the Voyager balloon have demonstrated their crossability in this difficult situation.

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