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Limits: Publication Date from 2003/10/01 to
2005/02/01

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1: Appl
Radiat Isot. 2003 Oct;59(4):225-30.

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Automated preparation of
188Re-labeled radiopharmaceuticals for endovascular radiation
therapy.

Oh SJ, Moon DH, Lee WW, Park SW, Hong MK,
Park SJ, Shin DI, Lee HK.

Departments of Nuclear Medicine,
Asan Medical Center, University of Ulsan College of Medicine, 388-1
Pungnap-2dong, Songpa-gu, Seoul 138-736, South Korea.
[email-masked]

We have developed an automated system for
the preparation of highly concentrated 188Re-perrhenate,
diethylenetriamine pentaacetic acid (DTPA) and mercaptoacetyltriglycine
(MAG3). The three procedural steps include concentration of
188Re-perrhanerate, chelation and purification and sterilization. The
steps are operated by a small micro-controller. The eluted
188Re-perrhenate of 15 GBq/18 ml from 37 GBq 188W/188Re-generator was
concentrated to 1.2 ml in 10 +/- 0.5 min with a recovery yield of 95 +/-
1.5%. We obtained the highest radiochemical yield of 95.4 +/- 2.8% and
98.5 +/- 1.2% for 188Re-DTPA and MAG3 at the oil bath temperatures of
95-97 degrees C and 93-97 degrees C, respectively.

Publication
Types:

Evaluation Studies

Validation Studies

PMID: 14522229 [PubMed - indexed
for MEDLINE]

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