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Limits: Publication Date from 2003/10/01 to
2005/02/01

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1: J Am
Soc Echocardiogr. 2004 Sep;17(9):933-40.

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Diagnosis of viable
myocardium using velocity data of Doppler myocardial imaging: comparison
with positron emission tomography.

Yang HS, Kang
SJ, Song JK, Moon DH, Song JM, Kang DH, Lee CW, Hong MK, Kim JJ, Park
SW, Park SJ.

Division of Cardiology, Asan Medical Center,
University of Ulsan, College of Medicine, Seoul, South Korea.

To
test whether velocity data of Doppler myocardial imaging (DMI) at rest
is useful for diagnosis of myocardial viability, 25 consecutive patients
(age 64 +/- 10 years) with regional wall-motion abnormalities at the
left anterior descending coronary artery territory and left ventricular
dysfunction (ejection fraction: 31 +/- 7%) underwent both DMI at rest
and positron emission tomography. The peak systolic velocity (Vpeak) and
postsystolic thickening (PST) velocity were measured in myocardial
segments of left anterior descending coronary artery territory from
apical views. A total of 71 segments were classified by positron
emission tomography as normal or viable in 38 (group A) and nonviable in
33 (group B). Although Vpeak did not show any difference between groups
(1.81 +/- 1.77 vs 1.29 +/- 0.94 cm/s, P =.107), PST velocity was
significantly higher in group A (2.48 +/- 1.68 vs 0.89 +/- 0.72 cm/s, P
<.001). The sensitivity and specificity of PST velocity > 2.0 cm/s
for diagnosis of viability were 61% (23/38) and 97% (32/33),
respectively. In segments with PST velocity was < or =2.0 cm/s, Vpeak
> 1.8 cm/s could discriminate group A from B with a sensitivity of
67% (10/15) and a specificity of 91% (29/32). The algorithm using both
PST velocity and Vpeak of DMI showed sensitivity and specificity of 87%
and 88%, respectively, for diagnosis of myocardial viability. Velocity
data of DMI at rest provides robust information regarding viability in
selected patients, and an advantage of this technique is that no stress
testing is needed.

PMID: 15337957 [PubMed - indexed for MEDLINE]

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